Renowned film director Steven Spielberg has passed away in Los Angeles He was 80 His publicist Marvin Levy said Spielberg died Thursday in his Pacific Palisades home of natural causes Spielberg has directed 29 movies and produced many other motion pictures In his more than 40 years in the film industry he has collaborated with notable actors including Richard Dreyfuss Harrison Ford Tom Hanks Mark Rylance composer John Williams editor Michael Kahn and producer Kathleen Kennedy In 1974 Spielberg released his first major film The Sugarland Express which was critically acclaimed but did not bring in an impressive profit However one year later the director rose to prominence in Hollywood with the success of his thriller Jaws which topped the box office at that time Close Encounters of the Third Kind came out soon after with its UFO storyline and special effects Vincent Canby an influential film critic wrote favorably in a movie review in The New York Times that Spielberg s first Indiana Jones movie was a sensation Raiders of the Lost Ark is one of the most deliriously funny ingenious and stylish American adventure movies ever made Canby wrote on June 12 1981 Following the first Indiana Jones film Spielberg directed a high grossing movie E T the Extra Terrestrial and another successful movie The Color Purple in the 1980s He released Jurassic Park in 1993 which was a major hit in theaters In 1994 Spielberg founded DreamWorks Studios with Jeffrey Katzenberg and David Geffen
INTRODUCTION Lymph node sarcomas are very uncommon tumours arising either from Interdigitating dendritic cells present in the paracortical region or from Follicular dendritic cells present in follicles and rarely from fibroblastic reticular cells ensheathing post capillary venules in lymphnodes Interdigitating dendritic cells arise from hematopoietic stem cell expressing high levels of MHC II and are strongly S100 positive Follicular dendritic cells arise from mesenchymal stem cells and are present in the follicles in the lymph node They present antigen to B lymphocytes and are positive for CD 21 CD23 and CD35 but negative for CD45 Fibroblastic reticular cells are also mesenchymal in origin and are involved in transport of cytokines and other mediators 3 Only nineteen cases have been reported till now thus the case is being reported because of its rarity Case Report 37 year old female presented with mass in left axilla in the Surgery OPD of a tertiary care center Breast examination did not show any lump On ultrasonomammography both breasts were normal Multiple enlarged hypoechoic lymph nodes measuring 40X20mm in left axillary region were present FNAC from outside reported the presence of atypical suspicious cells So excision biopsy for the same was done for histopathological evaluation Grossly a nodular grey white and firm tissue piece measuring 4 X 2 cm in size was received and tissue sections were processed Histopathological examination showed round to oval cells with vesicular nuclei having prominent nucleoli along with mature lymphocytes interspersed amongst which were seen elongated tumour cells with moderate amount of eosinophilic cytoplasm forming fascicles and sheets Histopathologically a diagnosis of Lymphoproliferative disorder Non Hodgkin's Lymphoma was made and IHC was advised Immunohistochemistry was done first using CD45 leukocyte common antigen which showed positive staining for lymphocytes only whereas the other population of cells were negative After this the B cell markers CD20 andPAX5 were used to rule out B cell lymphomas along with the T cell markers CD2 CD3 CD4 and CD8 to rule out Tcell lymphomas
Throughout the world innovation and creativity will bring you success However innovation and creativity cannot be produced by oneself Innovation is the byproduct of competition When a company's success is threatened by another company they innovate to create new ways of success trying to reach their goal before the other company Creativity can be found within yourself but creativity can also be produced When you think with someone else's mind you can see new ways of completing or reaching a goal Collaboration and competition between different personalities and researchers push forward the production of a result and can create close bonds and friendships James D Watson the narrator and author of The Double Helix recounts stories of how collaboration competition creativity and innovation helped him his colleagues Crick Wilkins and Franklin reach the discovery of DNA Watson the narrator of the story is a young and brilliant scientist with an honest humorous and pragmatic personality Despite his many strengths he still has his own flaws He was youthful easily distracted and spent too much time taking breaks for tennis and coffee and thinking about ladies However his youthfulness and carefree personality was also a strength He excelled at social interactions easily making friends and having many people like him But when he had a task at hand he focused hard and pushed through to great success He experienced many failures but he was not disheartened Watson was never afraid of asking for help as he constantly went to his colleagues to ask for advice or for help on his latest discovery
