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355REVIEW OF LITERATURE Padashetty SA et al 2007 performed phytochemical analysis of E echinatus and turned out to contain isoflavones triterpenoids phenolic compounds glycosides and alkaloids Various parts of the plant such as roots leaves flowers and other aerial parts were used for the extraction of a variety of phytoconstituents Singh S Upadhyay RK et al 2006 found that alkaloids were present in the aerial parts of plant like echinopsine echinopsidine and quinazolinone While study of seeds of echinops echinatus revealed the presence of echinacin Apigenin and its derivatives Taraxasterol acetate and echinaticin in them Chaudhuri PK et al 1986 after phytochemical analysis found a new glycoside i e echitin I and Apigenin in the plant Dan He et al 2017 furthermore discovered little amount of alkaloid 7 hydroxy echinozolinone I Oksana Sytar et al 2017 worked on Echinops species Echinops echinatus
Echinops niveus and Echinops integrifolius and proposed that they contain the fair amounts of flavonoids in them Yadava R N et al 2006 Other flavonoids like Kaempferol kaempferol 4 methylether kaempferol 7 methylether kaempferol 3 O alpha L rhamnoside myrecetin 3 O alpha L rhamnoside Dihydroquercetin 4 methyl ether 5 7 8 4 dimethoxyflavanone 5 O L rhamnopyranosyl 7 O D arabinopyranosyl 1 4 O D glucopyranoside also found in the plant An anti inflammatory active flavanone glycoside alongwith a known compound dihydroquercetin 4 Me ether is also reported from leaves Four phenolic compounds apigenin apigenin 7 O glucoside echinacin I and echinaticin II are reported from E echinatus A Nahata et al 2013 worked on antiandrogenic activity of the plant and it could be employed for a number of reproductive and excretory system disorders like the prohibition of delivery and abortions in unintended urinary discharges a diuretic and in syphilis It showed pronounced antiandrogenic properties MATERIALS AND METHODS Collection and identification of plant The plant was collected from Multan in adequate amount Then it was identified from the agronomy department and Voucher specimen was preserved as well