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Acute eosinophilic pneumonia AEP is Rare

Introduction Acute eosinophilic pneumonia AEP is rare It often results in acute Respiratory failure with an attended mortality Acute eosinophilic pneumonia is characterized by infiltration of pulmonary parenchyma with eosinophilic infiltrates and often associated with peripheral eosinophilia 1 2 It has been associated with antibiotics certain chemicals and Non steroidal anti inflammatory agents 3 The pathophysiology of AEP involves detection of the offending agent by alveolar macrophages which presents the antigen to T helper cells which in turn produce interleukin 5 that along with eotaxin produced by endothelial cells epithelial cells macrophages and airway smooth muscle cells result in accumulation of eosinophils in the alveolar spaces This in turn results in acute epithelial injury5 We present a patient with AEP following therapy with Daptomycin Case Report 



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