The solution of methylcellulose is having a special gelation phenomenon that commonly occurs by heating it so that it can change to gel and by cooking in order to form a clear solution Hirrien et al 1996. An increase in the viscosity of solution the gelation temperature of a given degree of substitution gets decreases with the addition of electrolytes lowers the gelation temperature Brandt 1986. The quantities of salts added also affected it. A few of these salts played a lead role in the prevention of dissolution of methylcellulose at ambient temperature Levy and Schwarz 1958. The addition of electrolytes and the procedure of heating destroy the hydrated structure. During this hydrogen bond between water and the polymer gets broken. When polar water mixed with organic solvents for instance alcohol or glycols are added then the solution of Methylcellulose gets stabilized Kundu et al 2003. Methylcellulose and the polar additives form strong hydrogen bonds which increase gelation temperatures and able to create more stable soluble complexes in the solution Brandt 1986 Kundu et al 2003.
Treatment. The main aim of the treatment is to get the blood counts back to normal. If this is achieved and the bone marrow looks healthy under the microscope the cancer is said to be in remission i.e the absence of any detectable cancer cells in the body. Over the past decade's effective treatments for acute lymphoblastic leukemia have been developed, hence survival rates have increased. There are many treatments available for ALL including steroids, chemotherapy, radiation, therapy, stem cell or bone marrow transplants etc www mountsinai org 37. Chemotherapy is the first treatment of choice with a goal of achieving a remission. There are three stages in chemotherapy. A remission induction, B intensification, and C maintenance therapy. A Remission Induction. The major goals are 1 Rapidly kill all the tumor cells and restore normal hematopoiesis, 2 Reduce blast cells in the bone marrow to 5 and eliminate tumor cells from blood, 3 Cause absence of other symptoms of the disease. The following drugs are used in combination steroids like dexamethasone, vincristine, asparaginase etc Hoffbrand et al 2013 38. B Intensification High doses of chemotherapy is helpful in removing the tumor burden.