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From forgetting names to forgetting the reason for entering a room Lapses

From forgetting names to forgetting the reason for entering a room lapses in memory are normal and do not hinder everyday life Problems arise when memory deficits begin to impact ordinary life Amnesia is a memory deficit that can be defined as complete or partial memory loss Ryan et al 2000 often resulting from lesion operations or brain injuries such as strokes Two distinct types of amnesia exist retrograde and anterograde Retrograde amnesia are unable to recall memories of events that occurred before the brain damage They are however able to form new memories following the damage Nadel Moscovitch 1997 The opposite is true for anterograde amnesics Marslen Wilson Teuber 1975 These two types can co occur in one patient or occur individually displaying dissociations between the two Patient HM arguably the most famous amnesic patient had almost complete absence of anterograde memory and partial retrograde loss Scoville Milner 1957 These deficits were caused due to the removal of a large area of his medial temporal brain area as treatment for epilepsy Alongside the establishment of HM s memory deficits two opposing models to explain amnesia emerged 



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HIV a member of the genus Lentivirus

Human immunodeficiency virus HIV a member of the genus Lentivirus of the family Retroviridae has become a global pandemic Campbell et al 2005 The alarming statistics surrounding HIV 1 in South Africa S A alone has shown a prevalence of 5 51 million individuals infected with HIV 1 South African National HIV 1 prevalence 2014 Evidence supports that the high rate of HIV 1 prevalence in S A is accompanied by increased antiretroviral ARV drug consumption Transer et al 2013 Despite the positive outcomes of ARV usage studies have indicated that they attribute to deleterious long term effects on the central nervous system CNS Transfer et al 2013 thus prompting further research into HIV 1 progression within the brain as well as seeking out different treatment modalities for HIV 1 patients The CNS is an important target of HIV 1 infection and its associated neurological impairment Atluri et al 2015 It comprises of glial cells macroglia and microglia and astrocytes Guduru et al 2013

1 pages | 298 words
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