Animal research has played a vital part in nearly every medical breakthrough over the last 100 years according to The California Biomedical Research Association https animal testing procon org Also Understanding Animal Research stated that nearly every Nobel prize winner in Physiology or Medicine since 1901 has relied on animal data for their research The first Nobel prize winner to use animal testing was Emil von Behring who was awarded in 1901 for his work in 1898 in which he used a mix of toxin and antitoxin in horses to create immunity against diphtheria https www nobelprize org Some other examples of medical advances that used animal testing are HIV cancer asthma vaccines antibiotics high blood pressure and organ transplants according to the CBRA http www ca biomed org Animals are very genetically similar to humans chimpanzees share 99 of DNA with humans and mice share 98 http www ca biomed org They share common systems circulatory nervous etc and organs heart lungs etc that work very similar to the human version if not almost identically