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Liver is most commonly involved by metastatic diseases due to its enriched connectivity with the blood vessels and lymphatic vessels being liver cancer one of the leading causes of death worldwide Tumor volume measurement accurate staging analysis tumors features such as site local spread distant and involvement with other organs in the body and early detection are decisive to improve the curability and cancer follow up helping the physician to decide what type of treatment is best suited and to predict patient s prognosis In the field of medical diagnosis an extensive diversity of imaging techniques have been incorporated such as ultrasound imaging computed tomography CT and magnetic resonance imaging MRI The development of image processing and segmentation techniques plays an important role in allowing the extraction of metastatic liver tumor from the surrounding tissue Manual segmentation is time consuming prone to errors dependent on users and requires expert knowledge to yield accurate and robust results Therefore CAD Computer Aided Diagnosis oriented diagnosis has become one of the most extensive research fields
