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301Organs That are affected by the Vaccine Diphtheria infects the throat nose and larynx the toxin can also affect the heart kidneys liver lungs nerves and muscles therefore the vaccine will need to affect the lymphatic system to allow the immune system to work and also the organs that are affected by the toxin so therefore no symptoms can occur Uptake of Diphtheria Vaccine UK In the UK children receive three primary doses of Diphtheria for full immunisation to occur The WHO target of 95 means that if 95 of the population is vaccinated that means that the whole nation will be immune to the Toxin 93 4 of children in the UK were vaccinated which was a slight drop from 2015 16 of 93 6 In the year 2012 13 94 7 of children at 12 months had their primary treatment of the 5 in 1 vaccine Screening Immunisations Team NHS Digital 2017 The effectiveness of Vaccine The Diphtheria vaccine has been very effective in recent years in many countries In the UK nearly 95 of babies at 12 months have the vaccine which has made Diphtheria very rare in the UK However recently the number of cases of Diphtheria in the Russian Federation rose during 1991 1992 with 319 respiratory diphtheria cases in children between the ages of 6 years to 14 years Control subjects at that time received more doses of the vaccine The results that were taken during that time shows that the vaccine was very effective even if one dose was taken Bisgard K et al 2018